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KMID : 0363220190570090532
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Korean Journal of Dermatology
2019 Volume.57 No. 9 p.532 ~ p.537
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Rapidly Involuting Congenital Hemangioma: Five Case Reports
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Han Man-Hoon
Chung Ho-Yun
Lee Jong-Min
Huh Seung
Kim Jun-Young
Lee Weon-Ju
Lee Seok-Jong
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Abstract
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Rapidly involuting congenital hemangioma (RICH), a subtype of congenital hemangioma (CH), is fully developed at birth and undergoes rapid involution by 6-14 months of age. Clinically, this vascular lesion differs from both non-involuting CH and infantile hemangiomas. It is important to distinguish between this rare condition and other vascular lesions to ensure appropriate management (active intervention vs. non-intervention). We describe 5 patients diagnosed with RICH based on clinicopathological and/or imaging studies. Three patients showed red-stippled bluish to purplish tense plaques and two showed slightly depressed red-stippled hypopigmented rubbery patches at their initial visit. Spontaneous involution commenced shortly after birth, and complete involution occurred by 16.0±9.9 months of age. Doppler ultrasonography and magnetic resonance imaging were performed for further evaluation. Histopathological examination revealed vascular lobules of various sizes without true arteriovenous microfistulae, and thickened intra- and interlobular vessels were prominent with glucose transporter isoform-1 protein negativity.
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KEYWORD
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Congenital hemangioma, GLUT-1, Rapidly involuting congenital hemangioma, RICH
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